Understanding Addiction: Guide to How Addiction Really Works

What are Co-Occurring Disorders

Addiction is one of the most misunderstood health conditions. It is often mistaken for a lack of willpower or a moral failing, when the reality is far more complex. Understanding addiction means looking at how substances and certain behaviors change the brain over time, why some people are more vulnerable than others, and how those changes make stopping so hard. This guide explains what the science says in plain language, so you can better understand your own situation or that of someone you love, and take a clearer next step toward help through addiction therapy. Radix Recovery provides our integrated treatment program for people whose symptoms and substance use feed each other.

If you want to go deeper on any single topic after reading, you can browse our full library of addiction guides for more focused articles.

What Is Addiction?

Co-Occurring Disorders

Addiction is a chronic condition in which a person keeps using a substance or engaging in a behavior despite harmful consequences. It is marked by compulsive behavior that becomes difficult to control even when a person genuinely wants to stop. The American Psychiatric Association classifies these patterns as substance use disorders in the Diagnostic and Statistical Manual of Mental Disorders, better known as the DSM-5 [1], which is why substance use disorders are recognized as mental health conditions rather than character flaws.

The word covers more than illegal drugs. Substance addiction includes alcohol and opioids as well as many other drugs, and the DSM-5 also recognizes gambling disorder as a behavioral addiction. Some behavioral patterns, such as compulsive gambling, involve the same reward circuitry as drugs. Others often described casually as addictions, like shopping, are not formally recognized diagnoses, though they can still cause real distress.

Because these conditions are health conditions, they respond to treatment. Effective medications are available for alcohol and opioid use disorders, and behavioral treatments help people change the patterns that keep addiction going.

Understanding Addiction as a Brain Condition

Integrated Treatment Approaches

To really grasp how addiction works, it helps to see it as a brain condition. Addictive substances flood the brain’s reward system with dopamine, the chemical tied to pleasure and motivation. Dopamine release in the brain’s pleasure center is part of what reinforces substance use, teaching the brain to seek the substance again. This is sometimes described as a hijacking of a normal learning process, since the brain is wired to repeat rewarding experiences.

Over time, addiction changes brain structure and function. With repeated exposure, the brain adapts by producing less dopamine or reducing the number of receptors, so the same amount of a substance produces less of an effect. That adaptation is the basis of tolerance, in which a person needs more to feel the same effect. It also helps explain why addiction exerts such a long and powerful influence, and why cravings can persist even after years of sobriety. Nerve cells that once fired in response to natural rewards become less responsive, which can leave everyday life feeling flat during early recovery.

None of this means change is impossible. The brain retains the ability to heal and rewire, which is a core reason treatment works.

What Causes Addiction?

There is no single cause. Addiction is influenced by a combination of genetic, environmental, and developmental factors, and how they interact differs from person to person. Understanding how addiction develops means holding several of these factors at once rather than looking for one explanation.

The table below summarizes the main contributing factors.

FactorExamplesWhy it matters
GeneticFamily history of addiction, inherited traitsGenes account for a substantial share of vulnerability
EnvironmentalHigh-stress environments, upbringing, peer pressureShapes exposure and coping patterns
DevelopmentalEarly experimentation, adolescenceEarly use raises later risk
PsychologicalTrauma, childhood abuse, co-occurring mental health problemsCan drive substance use as a form of coping

The Role of Genetics and Family History

Genetic factors contribute meaningfully to the risk of addiction. According to the National Institute on Drug Abuse, genes, including the effects of environmental factors on gene expression, account for roughly 40 to 60 percent of a person’s risk of addiction [2]. That is why a family history of substance use raises risk, though it is not destiny. Genes influence how a person’s brain responds to substances and stress, but they interact with everything else in a person’s life.

Environmental and Developmental Factors

Environmental influences include upbringing and exposure to high-stress environments, both of which shape vulnerability. Peer pressure, availability of drugs and alcohol, and unstable home life all play a role. Developmental timing matters too. Experimenting with drugs or addictive behaviors at an early age increases the likelihood of addiction, because the adolescent brain is still developing the systems that govern judgment and self-control. Childhood experiences such as abuse or neglect also increase addiction risk.

Addiction and Mental Health Disorders

Addiction often co-occurs with other mental health disorders, and the relationship runs in both directions. Co-occurring mental health conditions like depression and anxiety can contribute to substance use, and substance use can worsen mental health problems. Individuals with anxiety or mood disorders are roughly twice as likely to experience a substance use disorder, and conditions such as bipolar disorder and post-traumatic stress disorder frequently overlap with addiction.

The overlap with trauma is especially strong. Among people with PTSD, estimates suggest that roughly 30 to 50 percent also have a co-occurring substance use disorder, and the figure runs higher in treatment-seeking and veteran populations [3]. Because untreated mental health issues can undermine recovery, integrated treatment that addresses both addiction and coexisting mental health issues at the same time is widely recommended. If you are unsure whether this applies to you, our guides on the most common co-occurring disorders with addiction, the signs you may need dual diagnosis treatment, and the connection between trauma and addiction go further.

It is worth being precise about terms. Comorbid and co-occurring are often used interchangeably, and our article on the difference between comorbid and co-occurrence explains the nuance. The broader question of whether addiction is a mental disorder is one many people ask, and the DSM-5’s classification is the reason the answer is generally yes.

How Common Is Addiction?

Addiction is far more common than many people realize. Among people aged 12 and older in the United States, recent national survey data indicate that roughly 1 in 6 met the criteria for a substance use disorder in a given year [4]. Alcohol use disorder is the most common single substance use disorder in the country. These numbers are a reminder that addiction is a widespread health issue rather than a rare or isolated problem, which is one more reason to treat it as a medical condition rather than a personal failing.

Types of Addiction

Not all addictions look the same, though they share common features. Broadly, they fall into two groups.

  • Substance addictions involve addictive drugs and other psychoactive substances, including alcohol, opioids, stimulants, and, in some cases, volatile substance abuse such as inhalants. These are the patterns most people picture when they think of drug addiction.
  • Behavioral addictions involve compulsive engagement in a rewarding behavior despite adverse consequences. Gambling disorder is the clearest formally recognized example, and it can involve consequences like spending money a person cannot afford to lose.

Whatever the form, the underlying pattern is similar: a behavior that once felt rewarding becomes compulsive and hard to stop. Our overview of the most common types of addiction impacting veterans and the piece on why some drugs are harder to quit than others explore how different substances behave.

How to Recognize Addiction

Learning to recognize addiction is a practical skill for anyone worried about themselves or a loved one. Because addiction is a chronic brain disorder, its signs show up across a person’s thoughts, body, and behavior. Physical symptoms can include changes in sleep, energy, and appearance, and withdrawal symptoms can appear when use stops or slows.

Common warning signs include:

  • Loss of control over drug use or drinking, and continued use despite harmful consequences
  • Tolerance, needing more of a substance to feel the same effect
  • Withdrawal symptoms such as irritability, anxiety, nausea, or depression when not using
  • Neglecting responsibilities, relationships, or interests
  • Legal problems, money problems, or health problems tied to use
  • Strong cravings and unsuccessful attempts to cut down

No single sign confirms addiction on its own, but a cluster of them over time is a strong signal. Our guides on the stages of addiction denial, the five stages of addiction, and the difference between a habit and an addiction can help you tell the difference. It also helps to understand the distinction between addiction and dependence and between physical and psychological dependence.

How Professionals Diagnose Addiction

To diagnose addiction, health care providers and addiction medicine specialists use the criteria in the Diagnostic and Statistical Manual of Mental Disorders. Rather than relying on a single test, a mental health professional or an alcohol counselor evaluates patterns of use, loss of control, and the impact on a person’s life. This structured approach helps distinguish a substance use disorder from occasional use or drug misuse, and it guides an appropriate treatment plan.

How Addiction Is Treated

Addiction is treatable, and most people do best with a plan built around their specific needs. There is no one-size-fits-all path, but several evidence-based treatment options are well established. For many people, the first step is a professional assessment that leads to a personalized plan.

Depending on the substance and severity, treatment may include:

  • Detox, which may be necessary for withdrawal from alcohol and benzodiazepines, since those withdrawals can be medically serious and sometimes require medical supervision
  • Medication, which is a core, evidence-based treatment for opioid use disorder and is also available for alcohol use disorder
  • Behavioral therapy, such as cognitive behavioral therapy and other talk therapy, which helps people build new coping skills and change the patterns that caused addictive behavior
  • Residential treatment or rehab services, along with outpatient care, matched to a person’s needs
  • Support groups, including 12-step programs like Alcoholics Anonymous, which support recovery efforts through shared experience

For opioid use disorder in particular, medication should be offered as a standard of care, and counseling can add benefit depending on a person’s needs. Program length varies with the individual, so while some residential programs run a few weeks, treatment length should follow clinical need rather than a fixed number of days. People who want to know when to act can start with our guide on the signs you need to seek help for addiction.

How Addiction Affects Families

Addiction rarely affects only one person. Communication difficulties and emotional strain are common in relationships affected by addiction, and family members often carry stress, worry, and hurt of their own. Learning about the condition helps loved ones respond with support rather than blame, which is why family involvement can strengthen recovery.

Families sometimes struggle to know whether a problem exists at all. Our guides on how to know if your loved one is using drugs, the importance of family education for addiction treatment, and the underlying reasons for addiction can help families understand what they are seeing and how to help. In some situations, people also ask about a court-ordered evaluation, which is another path into assessment and care.

What Recovery Looks Like

Recovery is not simply stopping substance use. It involves rebuilding a meaningful life, repairing relationships, and developing new coping skills to handle stress without turning to drugs or alcohol. Successful recovery can take time and effort, and setbacks can happen along the way. A return to use does not erase progress, but it is a signal to reassess a person’s plan and support.

Because withdrawal symptoms can vary in severity and cravings can linger, ongoing support matters. Support groups, therapy, and continued care all help people stay on track, and many find that recovery deepens over months and years rather than ending at a fixed point.

Understanding Addiction: Frequently Asked Questions

Is addiction a disease or a choice?

Neither label fits perfectly, but the weight of evidence treats addiction as a chronic brain disorder rather than a simple choice. The initial decision to try a substance may be voluntary, but once addiction develops, changes in brain structure and function make stopping far harder than willpower alone can manage.

Can the brain recover from addiction?

Yes, to a meaningful degree. The brain can heal and form new patterns over time, though some cravings and vulnerabilities may persist, which is why ongoing coping skills and support are valuable well into recovery.

When should someone seek treatment for addiction?

It is reasonable to seek treatment as soon as substance use is causing problems in health, relationships, work, or daily functioning, or when a person cannot cut down despite trying. Earlier help generally makes recovery easier, and a mental health professional can recommend appropriate treatment options.

Source List

  1. American Psychiatric Association, “What Is a Substance Use Disorder?” https://www.psychiatry.org/patients-families/addiction-substance-use-disorders/what-is-a-substance-use-disorder
  2. National Institute on Drug Abuse, “Drug Misuse and Addiction.” https://nida.nih.gov/publications/drugs-brains-behavior-science-addiction/drug-misuse-addiction
  3. U.S. Department of Veterans Affairs, National Center for PTSD, “Treatment of Co-Occurring PTSD and Substance Use Disorder.” https://www.ptsd.va.gov/professional/articles/article-pdf/id1635224.pdf
  4. Substance Abuse and Mental Health Services Administration, “2023 National Survey on Drug Use and Health.” https://www.samhsa.gov/data/report/2023-nsduh-annual-national-report

Dr. Jacob Christenson, PhD, MBA, LMFT

CEO, Radix Recovery

Dr. Jacob Christenson is CEO and a founding partner of Radix Recovery, where he leads clinical strategy and organizational vision. With more than 20 years of experience in behavioral health, he specializes in addiction treatment, family systems therapy, and complex mental health conditions.

He earned his PhD and MS in Marriage and Family Therapy from Brigham Young University and holds a BS in Psychology, magna cum laude, from California Polytechnic State University. Dr. Christenson is an approved clinical supervisor in Iowa and has authored more than 15 peer-reviewed journal articles.

Book Free Consultation

Newsletter Form

Speak With a Dual Diagnosis Specialist — Confidentially, Today

Table of Contents

Book Free Consultation

Newsletter Form

Written by

The Radix Clinical & Outreach Team

Our clinical and outreach team writes about recovery in plain, honest language to help people and their loved ones understand what treatment really looks like.

Medically reviewed by

Radix Recovery clinical leadership

Reviewed June 6, 2026
Clinical articles are reviewed by licensed clinicians on our team to help keep the information accurate, current, and responsible.

More Recovery Stories
Alcohol AddictionAddiction TreatmentText Post

What Happens to Your Brain When You Stop Drinking: A Day-by-Day Recovery Timeline

Long-term, heavy alcohol use can result in a thinning of the brain's cortex. The cortex is responsible for key functions such as decision making, emotion regulation, and self-control, and thinning may lead to difficulties in critical thinking and social interactions.

By the Radix Clinical & Outreach Team

Alcohol AddictionAddiction TreatmentText Post

“Alcoholic Personality”: Do Traits and Behavior Patterns Reveal Drinking Habits?

Researchers studying addictive behaviors have moved away from the notion of one fixed personality type that leads to alcoholism. Instead, they look at how certain personality traits, environmental factors, and brain chemistry interact.

By the Radix Clinical & Outreach Team

Alcohol AddictionAddiction TreatmentText Post

High-Functioning Alcoholic: Hidden Signs, Health Risks, and When to Get Help

A functional alcoholic may excel at work, hit deadlines, and look healthy on the outside. At the same time, the same person may rely heavily on alcohol after hours, hide bottles, or drink alone to take the edge off. The contrast between public image and private behavior is what makes

By the Radix Clinical & Outreach Team

Help Is One Call Away
Reading is a good first step. When you are ready to talk it through, our admissions team is here 24/7 to verify your benefits and help you find the next step, with no obligation.

Reading